An abomination refers to the blending of two or more supernatural creatures that are otherwise incompatible. The phrase was first coined to describe such an entity by White Wolf Publishing in their Storyteller system role playing game modules. By White Wolf's definition, an abomination is the end result of a cross-breed between a vampire and a werewolf. This term has also been used in the film Underworld.

The Abomination is also the code name used to describe Emil Blonsky, a comic book character featured in Marvel Comics titles who is usually presented as an adversary to the Hulk. Like the Hulk, Blonsky was mutated into a monster via exposure to intense levels of gamma radiation.

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